What do the commercial determinants of health look like for goods and services that are human rights? The CDoH refer to “the systems, practices, and pathways through which commercial actors drive health and equity”.1 Public health research, advocacy and policies seeking to understand the CDoH have focused primarily on a narrow segment of commercial actors selling harmful products such as tobacco, alcohol and ultra-processed foods. The attention given to these sectors is understandable, given the significant burden of morbidity and mortality associated with their production and consumption. Over time, the CDoH field has turned its attention to the role of other sectors of the economy, including gambling,2 firearms,3 incarceration,4 social media,5 automobiles6 and more. The field has also evolved to recognise other pathways through which commercial actors influence health beyond the products in their portfolios, including tax avoidance7 or the “extractive injustice” of land acquisitions by powerful multinationals in low income countries.8 Attention has also turned to the underlying systems and structural drivers that enable harmful commercial practices, such as neoliberalism, capitalism and privatisation.1, 9 One area that has seen little attention within CDoH scholarship, thus far, is analysis of industry sectors that provide goods and services linked to human rights, such as housing, education, and health care. Unlike tobacco or other discretionary products, access to these goods and services improves quality of life and are essential for good health and wellbeing in our society. Article 25 of the Universal Declaration on Human Rights states that “Everyone has the right to a standard of living adequate for the health and well-being of himself [sic] and of his [sic] family, including food, clothing, housing and medical care and necessary social services”.10 Australia is party to several human rights treaties, including those addressing the right to health.11 Important for our argument here, the United Nations’ elaboration on Article 25 stipulates that governments have an obligation to ensure that private sector activities do not undermine access to these goods and services (eg, to food or water).12 We argue that this should be scrutinised for compatibility with the privatisation and commercialisation of sectors that provide essential goods and services. In this perspective article, we consider how a CDoH lens extends to healthy goods and services, and what our so-called best buy interventions could look like. We focus on two sectors as examples: health care and housing. These sectors illustrate some of the harmful practices that companies engage in, as well as the structural forces that enable and reinforce those practices. Health care is a multitrillion-dollar global industry. Ostensibly, for-profit health care does not undermine patient wellbeing. However, evidence suggests that commercial profits often come at the expense of patients. Runner up in the 2022 annual Shkreli Awards (for the most egregious examples of profiteering and dysfunction in US health care) was a private equity acquisition of two rural hospitals (https://lowninstitute.org/projects/2022-shkreli-awards). The firm halted employee health insurance (despite deducting premiums from their salaries) and failed to ensure the hospital had sufficient supplies and drugs, while taking $20 million in federal funds. They then closed both hospitals. Examples like this are common. Perhaps the most prominent historic example of commercial determinants within health care has come from the pharmaceutical industry — an industry that has brought incredible innovation to the sector and benefit to society, but one that is also mired in commercially driven behaviours and practices that risk patient and clinician wellbeing and compromise health equity (Box 1). Structural influences, such as privatisation and commercialisation, have driven perverse incentives. In many countries, private health insurance, for instance, is defended as a way to save taxpayer money. Yet the flow of government subsidies into private insurers raises questions about whether this is the best or fairest use of public funds. In Australia, researchers have criticised the private health insurance rebate (approaching $7 billion annually) that might be otherwise invested in a universally accessible system.15 Market consolidation and integration has been increasing across the health care sector internationally. Even though this has the potential to bring efficiencies and other benefits, it also risks anticompetitive behaviour. Extensive research suggests that providers in more concentrated markets charge higher prices, and this burden falls on patients, not insurers, and it is often without accompanying gains in efficiency or quality.16 A 2018 review of US data concluded that hospital and physician consolidation threatened health service affordability and warranted urgent attention from antitrust authorities.17 Considerable academic attention has been devoted to the impact that Australia's mixed public–private health care system has on equity of access, including cost barriers.18, 19 However, the influence of other system-augmenting commercial determinants, such as privatisation, horizontal and vertical integration, and private equity, have received sparse academic or policy attention despite the threats they pose. We know privatisation, consolidation and integration have been increasing across primary care and specialties within Australia, but the scale and extent are unknown, as are system impacts and risks thereof.20 Housing is a human right and a key social determinant of health. Everyone's health is shaped by where they live, and housing-focused interventions have long been effective in protecting and improving population health and reducing health inequalities.21 Australia faces a housing affordability crisis. Relative to other countries, the cost of housing (either renting or owning) is high in Australia, resulting in classification of our housing as severely unaffordable (the worst category) on international rankings by Demographia.22 Young people, in particular, face housing affordability stress, generating intergenerational inequities within the housing market.23 The financial and social consequence of this is compounded by inadequate safety nets. Australia has a small social housing sector (about 4% of our housing stock) and long waiting lists for public housing.24 Not only is housing unaffordable in many of our urban centres but it can also often be in poor condition and energy inefficient (especially rental housing) (Box 2).25 What has been less well researched is how the scale of investment and wealth generation tied to housing in Australia positions it as a critical CDoH. The Australian housing market is a multitrillion-dollar asset. It generates profits to the private sector (including developers) and taxes for state governments (via stamp duty), and has made millionaires of many Australian homeowners. Most of this housing wealth is tied to residential real estate ($9.6 trillion) and superannuation and the stock market ($6 trillion combined).27 The tension between housing for social good and wealth creation pervades attempts to make changes in this sector. Strong lobbying by well resourced organisations (eg, the Property Council of Australia, which is an advocacy group for the property industry and comprises 2300 member organisations) against removing negative gearing (which would shift our framing of housing as investment) and introducing minimum apartment standards (which would reduce the incidence of problems such as mould and structural deficiencies in apartments) is a case in point.28, 29 The residential real estate sector has powerful allies in Australia's economy, including the banking sector, which is involved in superannuation and wealth management. A CDoH lens forces us to be clear about our vision for housing: should it be as a wealth creation tool or a social benefit, in which case housing cooperatives, social housing, and minimum standards in the rental sector should be the focus of discussion and part of a prevention strategy in public health. This requires a substantial change in our policy approach and a more explicit discussion of the commercial pressures to generate wealth through housing. As the CDoH field expands from a focus on harmful products to necessary goods and services that are deemed human rights, we must reflect on our current policy responses in public health, and whether and how we might repurpose them to fit new and different challenges. While we could put warning labels on unsafe houses, the reality is that many people lack the resources to move somewhere better. Education and counselling initiatives to inform people about the importance of good quality housing or health care are useless without secure and affordable access to these essential services irrespective of the social and economic circumstances of users. This requires system level change.30 In Box 3, we propose a set of pan-industry interventions that could address CDoH, whether the product is harmful or the service is considered a human right. The examples come from other sectors that have received more attention to date. Where possible, we have indicated the relevance for health care and housing. Thinking about CDoH in terms of essential services, such as health care and housing, highlights opportunities and challenges for advancing an agenda to address CDoH. First, it is important to look beyond specific products to their producers, manufacturers, retailers and investors; that is, identify the organisations who profit. Moving upstream in this way, from product or service to commercial actor, reveals similarities in the strategies and practices of commercial actors irrespective of the sector (for a more detailed analysis, see the 2023 Lancet series1). Second, we must understand and harness the diversity within industry sectors.32 The commercial world comprises for-profit and not-for-profit organisations, quasi-commercial statutory organisations, foundations and more; depending on their legal form, portfolios and resources, these organisations will have different incentives, accountability mechanisms, and impacts on health.32 Organisations that promote health should be identified, supported and scaled-up. Finally, we need better data. It is challenging (and often expensive) to access information about corporate political activity, company structures, revenue and market share, and other data that help to map out and understand the attributes and practices of commercial actors. For instance, in the health care sector, Australia's performance against other countries in the relative value of our pharmaceutical expenditure is visible. Other commercial health care activity — corporatisation of primary care, public–private partnerships, private equity and/or foreign investment — has far less visibility. Better data are vital to understand the impacts of privatisation on health care, housing, and CDoH more generally, and whether the pursuit of profits is compromising the human right to health. Commercial determinants often undermine health and health equity.1 It is possible to redesign our systems so that health is prioritised over profiteering. We identify nine types of interventions that act at the systems level, moving the focus from people to structures and organisations. This shift in focus (and the way we think about commercial determinants) is essential, we argue, if we want to address their effect on people's access to essential goods and services — here illustrated through the lens of health care and housing. Open access publishing facilitated by The University of Melbourne, as part of the Wiley - The University of Melbourne agreement via the Council of Australian University Librarians. Jennifer Lacy-Nichols is the recipient of a Fellowship from the Victorian Health Promotion Foundation. Adam Elshaug is Ministerially appointed to the Strengthening Medicare Taskforce and the Medicare Benefits Schedule Review Advisory Committee (MRAC); is health economic and policy advisor to Cancer Australia; is a member of the Research Partnership Advisory Group (translational research priorities 2022–24), Victorian Government Department of Health; is a member of the Victorian Perioperative Learning Health Network Advisory Group (Safer Care Victoria);and holds grants from the National Health and Medical Research Council and the Medical Research Future Fund. Commissioned; externally peer reviewed.